Mike C. L. Wu

Mike (Chia Lun) is a senior research fellow at the Heart Research Institute and Charles Perkins Centre at the University of Sydney (NSW). He completed his undergraduate Bachelor of Science degree in 2006 and received first-class honors in Biomedical Science in 2008 from Queensland University. In 2013, he completed his doctoral studies in immunopharmacology at the University of Queensland under an Australian Postgraduate Award. With a vision of translating new therapeutic treatments and medical diagnostic tools, Mike obtained a graduate certificate in research commercialization in 2012 at Queensland University and worked at UniQuest in technology commercialization and patenting activities in 2013. He joined Prof. Shaun Jackson's lab at The Australian Centre for Blood Diseases, Monash University in 2013 to enhance understanding of the basic principles of normal hemostasis and its diseases in cardiovascular diseases. In 2015, Mike joined HRI and, under Prof. Jackson's supervision, led a team to establish animal models, contributing as a first author to a landmark publication in Science Translational Medicine in 2017. In 2016, his research findings and interests laid the foundation for further basic and translational research through collaboration with Prof. Payne at the School of Chemistry, University of Sydney. In 2016, he also contributed to two successful NHMRC project grants (APP1127278 and APP1120941). In 2017, he initiated a small project to understand the pathogenesis of microvascular obstruction in ischemic injury through the University of Sydney Kickstart Grant. Since 2016, Mike has been liaising with the chemistry team in Sydney University, co-investigating novel drugs for the treatment of stroke, securing funding from the Brain Foundation in 2019, NHF-Vanguard in 2020, and MRFF-TTRA (1012). Currently, his biological team under Prof. Jackson’s supervision, in collaboration with the chemistry team, is working on developing novel anti-coagulants with a significantly safer bleeding profile for the treatment of stroke.