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The Mak Research Lab is focused on multiscale mechanobiology in cancer and development. We develop interdisciplinary approaches, integrating microfluidics, computational modeling, and novel experimental systems, to decipher the principles driving emergent mechanobiological phenomena from the molecular to multicellular scales, including structure formation and functionality of cytoskeletal networks, invasive behavior of tumor cells, and collective dynamics of tumors, organoids, and tissues. We aim to bridge the gap between molecular signatures and mechanical phenotypes, especially in cancer metastasis and tissue morphogenesis.
The Mak Research Lab is focused on multiscale mechanobiology in cancer and development. We develop interdisciplinary approaches, integrating microfluidics, computational modeling, and novel experimental systems, to decipher the principles driving emergent mechanobiological phenomena from the molecular to multicellular scales, including structure formation and functionality of cytoskeletal networks, invasive behavior of tumor cells, and collective dynamics of tumors, organoids, and tissues. We aim to bridge the gap between molecular signatures and mechanical phenotypes, especially in cancer metastasis and tissue morphogenesis.
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论文共 61 篇作者统计合作学者相似作者
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Shoham Benmelech, Thien Le, Maggie McKay, Jungmin Nam, Krupakar Subramaniam, Daniela Tellez, Grace Vlasak,Michael Mak
APL BIOENGINEERINGno. 2 (2024): 021502-021502
Journal of Nanobiotechnologyno. 1 (2023): 457-457
David Böhringer,Andreas Bauer, Ivana Moravec, Lars Bischof,Delf Kah,Christoph Mark,Thomas J Grundy, Ekkehard Görlach,Geraldine M O'Neill,Silvia Budday,Pamela L Strissel,Reiner Strick,
bioRxiv : the preprint server for biology (2023)
Xiangyu Gong,Zhang Wen, Zixie Liang,Hugh Xiao,Sein Lee, Thomas Wright,Ryan Y Nguyen, Alejandro Rossello,Michael Mak
bioRxiv : the preprint server for biology (2023)
bioRxiv (Cold Spring Harbor Laboratory) (2023)
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Xingjian Zhang, Xin Shi,Dingyao Zhang,Xiangyu Gong,Zhang Wen,Israel Demandel, Junqi Zhang,Alejandro Rossello -Martinez,Trevor J. Chan,Michael Mak
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