Dr. Bukrinsky's research focus is on HIV biology and inflammatory diseases. The following projects are pursued: i) analysis of cholesterol metabolism in HIV-infected cells; ii) design and analysis of anti-HIV compounds; iii) analysis of molecular mechanisms of HIV-1 translocation from the cytoplasm into the nucleus of infected cells; iv) studies on the role of a new pro-inflammatory factor discovered by Dr. Bukrinsky - extracellular cyclophilin - in inflammatory disease pathogenesis; v) studies of HIV infection of macrophages. Dr. Bukrinsky is also actively involved in education activities, including international programs with Russia and Australia.