Michael Depasquale - Lieber Institute for Brain Development

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个人简介

Michael Depasquale currently works at the Drug Discovery, Lieber Institute for Brain Development. Michael does research in Biochemistry and Pharmacology.

研究兴趣

论文共 14 篇作者统计合作学者相似作者

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Dietary L-3,4-dihydroxyphenylalanine (L-DOPA) Augments Cuticular Melanization in Anopheles Mosquitos While Reducing Their Lifespan and Malaria Parasite Burden

Emma Camacho,Yuemei Dong,Christine Chrissian,Radames J B Cordero, Raúl G Saravia,Yessenia Anglero-Rodriguez,Daniel F Q Smith,Ella Jacobs, Isabelle Hartshorn, Jose Alberto Patiño-Medina,Michael DePasquale,Amanda Dziedzic,Anne Jedlicka,Barbara Smith,Godfree Mlambo,Abhai Tripathi,Nichole A Broderick, Ruth E Stark,George Dimopoulos,Arturo Casadevall

Research square (2024)

引用0浏览0WOS引用

Identification and Characterization of a Blood-Brain Barrier Penetrant Inositol Hexakisphosphate Kinase (IP6K) Inhibitor

Tyler Heitmann,Gangling Liao,Glen Ernst,Michael Poslusney, Thomas van Kralingen, Ye Li, Megan Masi,Michael Depasquale,Ingrid Buchler, Huijun Wei,Gregory V. Carr, Evgeny Shlevkov, Mengsi Lu,Henning Jessen,James C. Barrow

JOURNAL OF MEDICINAL CHEMISTRYno. 16 (2024): 13639-13665

引用0浏览0WOS引用

The IP6K Inhibitor LI-2242 Ameliorates Diet-Induced Obesity, Hyperglycemia, and Hepatic Steatosis in Mice by Improving Cell Metabolism and Insulin Signaling

Sandip Mukherjee,Molee Chakraborty,Jake Haubner,Glen Ernst,Michael DePasquale,Danielle Carpenter,James C. Barrow,Anutosh Chakraborty

BIOMOLECULES（2023）

引用2浏览0WOS引用

Inhibition of Human Uracil DNA Glycosylase Sensitizes a Large Fraction of Colorectal Cancer Cells to 5-Fluorodeoxyuridine and Raltitrexed but Not Fluorouracil

Eric S. Christenson,Anthony Gizzi,Junru Cui,Matthew Egleston,Kyle J. Seamon,Michael DePasquale,Benjamin Orris,Ben H. Park,James T. Stivers

Molecular Pharmacology（2021）

引用3浏览0WOS引用

Membrane Bound Catechol-O-methytransferase is the Dominant Isoform for Dopamine Metabolism in PC12 Cells and Rat Brain

Yupin Su,Michael DePasquale,Gangling Liao,Ingrid Buchler,Gongliang Zhang,Spencer Byers,Gregory V. Carr,James Barrow,Huijun Wei

European journal of pharmacology（2021）

引用8浏览0WOS引用

Identification of Small-Molecule Inhibitors of Human Inositol Hexakisphosphate Kinases by High-Throughput Screening

Gangling Liao,Wenjuan Ye,Tyler Heitmann,Glen Ernst,Michael DePasquale,Laiyi Xu,Michael Wormald,Xin Hu,Marc Ferrer,Robert K. Harmel,Dorothea Fiedler,James Barrow,Huijun Wei

ACS pharmacology & translational science（2021）

引用20浏览0WOS引用

Novel, Non-Nitrocatechol Catechol-O-methyltransferase Inhibitors Modulate Dopamine Neurotransmission in the Frontal Cortex and Improve Cognitive Flexibility

Byers Spencer,Buchler Ingrid P.,DePasquale Michael,Rowley Helen L.,Kulkarni Rajiv S.,Pinder Lucy,Kolobova Anna,Li Cailian,Au Vinh,Akuma Daniel,Zhang Gongliang, Johns Hopkins School of Medicine,Cheetham Sharon C.

Psychopharmacology/Psychopharmacologia（2020）

引用8浏览0WOS引用

Development of a PC12 Cell-Based Assay for in Vitro Screening of Catechol-O-methyltransferase Inhibitors

Gongliang Zhang,Ingrid P Buchler,Michael DePasquale,Michael Wormald,Gangling Liao,Huijun Wei,James C Barrow,Gregory V Carr

ACS chemical neuroscience（2019）

引用15浏览0WOS引用

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