Michael Carter

Cancer Research UK Cancer Therapeutics Unit and Division of Structural Biology The Institute of Cancer Research

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论文共 11 篇作者统计合作学者相似作者

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Exploiting Vector Pattern Diversity of Molecular Scaffolds for Cheminformatics Tasks in Drug Discovery

Daniela Dolciami,Robert M. Ziolek, Daniel W. Davies,Michael Carter,N. Yi Mok,Richard Sherhod

JOURNAL OF CHEMICAL INFORMATION AND MODELINGno. 6 (2024): 1966-1974

引用0浏览0WOSEI引用

Optimizing Shape Complementarity Enables the Discovery of Potent Tricyclic BCL6 Inhibitors

Owen A. Davis,Kwai-Ming J. Cheung,Alfie Brennan, Matthew G. Lloyd,Matthew J. Rodrigues,Olivier A. Pierrat,Gavin W. Collie,Yann-Vai Le Bihan,Rosemary Huckvale,Alice C. Harnden,Ana Varela,Michael D. Bright,Paul Eve,Angela Hayes,Alan T. Henley,Michael D. Carter,P. Craig McAndrew,Rachel Talbot,Rosemary Burke,Rob L. M. van Montfort,Florence Raynaud,Olivia W. Rossanese,Mirco Meniconi,Benjamin R. Bellenie,Swen Hoelder

Journal of medicinal chemistry（2022）

引用6浏览0WOS引用

Discovering Cell-Active BCL6 Inhibitors: Effectively Combining Biochemical HTS with Multiple Biophysical Techniques, X-ray Crystallography and Cell-Based Assays

Olivier A. Pierrat,Manjuan Liu,Gavin W. Collie,Kartika Shetty,Matthew J. Rodrigues,Yann-Vaï Le Bihan,Emma A. Gunnell,P. Craig McAndrew,Mark Stubbs,Martin G. Rowlands,Norhakim Yahya,Erald Shehu,Rachel Talbot,Lisa Pickard,Benjamin R. Bellenie,Kwai-Ming J. Cheung,Ludovic Drouin,Paolo Innocenti,Hannah Woodward,Owen A. Davis, Matthew G. Lloyd,Ana Varela,Rosemary Huckvale,Fabio Broccatelli,Michael Carter,David Galiwango,Angela Hayes,Florence I. Raynaud, Christopher Bryant,Steven Whittaker,Olivia W. Rossanese,Swen Hoelder,Rosemary Burke,Rob L. M. van Montfort

Scientific Reportsno. 1 (2022)

引用1浏览0WOSNATURE引用

Into Deep Water: Optimizing BCL6 Inhibitors by Growing into a Solvated Pocket

Matthew G. Lloyd,Rosemary Huckvale,Kwai-Ming J. Cheung,Matthew J. Rodrigues,Gavin W. Collie,Olivier A. Pierrat, Mahad Gatti Iou,Michael Carter,Owen A. Davis,P. Craig McAndrew,Emma Gunnell,Yann-Vai Le Bihan,Rachel Talbot,Alan T. Henley,Louise D. Johnson,Angela Hayes,Michael D. Bright,Florence Raynaud,Mirco Meniconi,Rosemary Burke,Rob L. M. van Montfort,Olivia W. Rossanese,Benjamin R. Bellenie,Swen Hoelder

JOURNAL OF MEDICINAL CHEMISTRY（2021）

引用7浏览0WOS引用

Achieving In Vivo Target Depletion through the Discovery and Optimization of Benzimidazolone BCL6 Degraders

Benjamin R Bellenie,Kwai-Ming J Cheung,Ana Varela,Olivier A Pierrat,Gavin W Collie,Gary M Box,Michael D Bright,Sharon Gowan,Angela Hayes,Matthew J Rodrigues,Kartika N Shetty,Michael Carter,Owen A Davis,Alan T Henley,Paolo Innocenti,Louise D Johnson,Manjuan Liu,Selby de Klerk,Yann-Vaï Le Bihan,Matthew G Lloyd,P Craig McAndrew,Erald Shehu,Rachel Talbot,Hannah L Woodward,Rosemary Burke,Vladimir Kirkin,Rob L M van Montfort,Florence I Raynaud,Olivia W Rossanese,Swen Hoelder

JOURNAL OF MEDICINAL CHEMISTRY（2020）

引用39浏览0WOS引用

Kinetic Optimization of Lysine-Targeting Covalent Inhibitors of HSP72

Jonathan Pettinger,Michael Carter,Keith Jones,Matthew D Cheeseman

JOURNAL OF MEDICINAL CHEMISTRY（2019）

引用34浏览0WOS引用

Introduction of a Methyl Group Curbs Metabolism of Pyrido[3,4- d]pyrimidine Monopolar Spindle 1 (MPS1) Inhibitors and Enables the Discovery of the Phase 1 Clinical Candidate N 2 -(2-Ethoxy-4-(4-methyl-4 H-1,2,4-triazol-3-yl)phenyl)-6-methyl- N 8 -neopentylpyrido[3,4- d]pyrimidine-2,8-diamine (BOS172722)

Hannah L Woodward,Paolo Innocenti,Kwai-Ming J Cheung,Angela Hayes,Jennie Roberts,Alan T Henley,Amir Faisal,Grace Wing-Yan Mak,Gary Box,Isaac M Westwood,Nora Cronin,Michael Carter,Melanie Valenti,Alexis De Haven Brandon,Lisa O'Fee,Harry Saville,Jessica Schmitt,Rosemary Burke,Fabio Broccatelli,Rob L M van Montfort,Florence I Raynaud,Suzanne A Eccles,Spiros Linardopoulos,Julian Blagg,Swen Hoelder

JOURNAL OF MEDICINAL CHEMISTRY（2018）

引用22浏览0WOS引用

Introduction of a Methyl Group Curbs Metabolism of Pyrido[3,4-d]pyrimidine Monopolar Spindle 1 (MPS1) Inhibitors and Enables the Discovery of the Phase 1 Clinical Candidate N²-(2-Ethoxy-4-(4-methyl-4H-1,2,4-triazol-3-yl)phenyl)-6-methyl-N⁸-neopentylpyrido[3,4-d]pyrimidine-..

Hannah L. Woodward,Paolo Innocenti,Kwai-Ming J. Cheung,Angela Hayes,Jennie Roberts,Alan T. Henley,Amir Faisal,Grace Wing-Yan Mak,Gary Box,Isaac M. Westwood,Nora Cronin,Michael Carter,Melanie Valenti,Alexis De Haven Brandon,Lisa O’Fee,Harry Saville,Jessica Schmitt,Rosemary Burke,Fabio Broccatelli,Rob L. M. van Montfort,Florence I. Raynaud,Suzanne A. Eccles,Spiros Linardopoulos,Julian Blagg,Swen Hoelder

Journal of Medicinal Chemistry（2018）

引用14浏览0引用

Privileged Structures and Polypharmacology Within and Between Protein Families

Joshua Meyers,Nicola E. A. Chessum,Salyha Ali,N. Yi Mok,Birgit Wilding,A. Elisa Pasqua,Martin Rowlands,Michael J. Tucker,Lindsay E. Evans,Carl S. Rye,Lisa O'Fee,Yann-Vai Le Bihan,Rosemary Burke,Michael Carter,Paul Workman,Julian Blagg,Nathan Brown,Rob L. M. van Montfort,Keith Jones,Matthew D. Cheeseman

ACS medicinal chemistry letters（2018）

引用16浏览0WOS引用

Inhibitors Of Mps1: Discovery Of Cct289346, A Highly Potent, Selective And Orally Available Preclinical Candidate

Hannah Woodward,Paolo Innocenti,Kwai-Ming J. Cheung,Sébastien Naud,Angela Hayes,Alan T. Henley,Amir Faisal,Grace Mak,Gary Box,Isaac M. Westwood,Michael Carter,Melanie Valenti,Alexis de Haven Brandon,Lisa O’Fee,Harry Saville,Rosemary Burke,Rob L. M. van Montfort,Florence I. Raynaud,Suzanne A. Eccles,Spiros Linardopoulos,Julian Blagg,Swen Hoelder

CANCER RESEARCH（2017）

引用0浏览0引用

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作者统计

#Papers: 11

#Citation: 216

H-Index: 7

G-Index: 9

Sociability: 5

Diversity: 1

Activity: 12

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