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Dr. Schachner discovered several seminal adhesion molecules important in the development of the nervous system, such as L1, CHL1 and the tenascins. She was among the first to recognize the importance of the functions of carbohydrates in cell recognition, being able to fine-tune cell interactions in the nervous system. One of many outstanding achievements was the discovery of signal transduction mechanisms mediated by recognition molecules expressed at the cell surface. Another important achievement was the finding that recognition molecules are important not only for nervous system development, but are also instrumental in regeneration after nervous system lesions and in shaping the activity of synapses. She was first to generate a knockout mutant for a neural recognition molecule, the P0 immunoglobulin-superfamily member involved in myelination in the peripheral nervous system. This study was seminal for the investigation of nervous system diseases.
A prolific researcher and writer, Dr. Schachner has published more than 800 articles in highly regarded journals. She has served on many academic and research boards. She is regarded internationally as one of the most successful women in neuroscience and is among the hundred most cited neuroscientists in the world.
A prolific researcher and writer, Dr. Schachner has published more than 800 articles in highly regarded journals. She has served on many academic and research boards. She is regarded internationally as one of the most successful women in neuroscience and is among the hundred most cited neuroscientists in the world.
研究兴趣
论文共 651 篇作者统计合作学者相似作者
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International journal of molecular sciencesno. 9 (2024): 4811
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCESno. 6 (2024)
Jaclyn T Eisdorfer, Josh Thackray,Thomas Theis,Ana Vivinetto,Matthew T Ricci,Sherry Lin, Olisemeka Oputa, Alana M Martinez, Hannah D Nacht, Monica Tschang, Malaika Mahmood,Ashley Tucker,
biorxiv(2024)
Haoyu Jiang, Anna O. Giarratana,Thomas Theis,Vini Nagaraj,Xiaofeng Zhou,Smita Thakker-Varia,Melitta Schachner,Janet Alder
Viviana Granato,Ludovica Congiu,Igor Jakovcevski,Ralf Kleene, Benjamin Schwindenhammer,Luciana Fernandes,Sandra Freitag,Melitta Schachner,Gabriele Loers
International Journal of Molecular Sciencesno. 6 (2024): 3408
Biomoleculesno. 5 (2023): 776-776
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