Prof. De Borst’s research focuses on the interaction between chronic kidney disease and cardiovascular complications. His main scientific aim is to identify targetable factors and innovative treatments to prevent progressive kidney function loss and the development of cardiovascular disease. So far, he has published >240 peer-reviewed articles that have been cited >7500 times. His work is embedded in several national and international research consortia, and is supported by national and European funding. He supervises a team of twelve PhD students, three post-docs, two research analysts and many students. He is (co-)Principal Investigator of several multicenter clinical trials and cohort studies, including the VARIETY national cohort study that aims to determine the diagnostic yield of exome sequencing in adults with unexplained chronic kidney disease, the K+ in CKD trial (clinicaltrials.gov NCT03253172) and the EFFECT-KTx study (NCT03769441). In 2020, he received the Stanley Shaldon award for young investigators from the European Renal Association (ERA).