He is a co-director and the technical lead for the LifeGuide project, a multidisciplinary initiative led by Professor Lucy Yardley that has attracted funding of well over £45 million (from MRC, EPSRC, ESRC, NIHR, EC and medical charities) for the development of online digital public health interventions such as weight management, hand hygiene and smoking cessation, as well as illness management interventions including diabetes, cancer, respiratory conditions and eczema.

In addition to online behaviour change initiatives, Mark's research interests include the application of Semantic Web technologies to pervasive systems and methodologies for the use of social media data to assist in disaster management. Mark has worked for a number of years in the area of information systems, from hypermedia systems for eLearning through to information infrastructures for multi-user pervasive experiences as exemplified by his work on the Equator IRC.