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个人简介
Dr. Shriver’s lab addresses questions related to recent human evolution -- in particular the evolution that took place during and after the spread of anatomically modern humans across the globe. Since it is clear from both physiological and genetic studies that all human populations have a very recent common origin, features (namely, genes and genetically determined traits and disease risks) that are different between populations are unique in having undergone evolution in the recent past. Some of the phenotypes Dr. Shriver’s lab focuses on include skin pigmentation, voice pitch and other sexually dimorphic traits, hair traits, facial features, preterm birth risk, adaptation to altitude, and type-2 diabetes risk. Most recently, Dr. Shriver’s lab has been collecting 3-D images of faces, analyzing the DNA of the photographed individuals, and printing, with a 3-D printer, images of the individuals’ faces.
Dr. Shriver’s lab uses methods of admixture mapping, which are well suited to the identification of genes that determine interpopulation differences in traits such as those listed above. Starting in the early 2000s, Dr. Shriver and his group made progress laying a foundation for understanding the population dynamics of admixed populations and the importance of population structure in making phenotype/admixture correlations detectible. His was one of the first groups to show with real data that the extensive population structure that results from admixture can be effectively controlled for using statistics.
研究兴趣
论文共 358 篇作者统计合作学者相似作者
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Christopher Nemeth,Hanne Hoskens, Graham Wilson, Mike Jones, Josef Dipietrantonio, Bukola Salami, Del Harnish, Peter Claes, Seth M. Weinberg,Mark D. Shriver,Benedikt Hallgrimsson
biorxiv(2024)
arxiv(2024)
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bioRxiv : the preprint server for biology (2024)
Meng Yuan,Seppe Goovaerts,Michiel Vanneste, Harrold Matthews,Hanne Hoskens, Ophir Klein,Richard Spritz,Benedikt Hallgrimsson,Susan Walsh,Mark Shriver,John Shaffer,Seth Weinberg,Hilde Peeters,Peter Claes
EUROPEAN JOURNAL OF HUMAN GENETICS (2024): 774-775
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bioRxiv the preprint server for biology (2024)
EUROPEAN JOURNAL OF HUMAN GENETICS (2024): 665-665
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Emma Young, Vince Battista, Melisa Kiyamu,Gianpietro Elias,Jenna Isherwood,Obed Garcia,Katarina Evans, Maria Inclan, Maria Rivera-Chira, Fabiola Leon-Velarde,Mark Shriver,Laurel Pearson,Tom D. Brutsaert, A. W. Bigham
AMERICAN JOURNAL OF BIOLOGICAL ANTHROPOLOGY (2024): 201-202
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EUROPEAN JOURNAL OF HUMAN GENETICS (2024): 784-784
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作者统计
#Papers: 357
#Citation: 21828
H-Index: 76
G-Index: 144
Sociability: 7
Diversity: 0
Activity: 1
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