Her group at Caltech played a key role in the discovery of the Higgs boson in 2012 and has been leading the design, R&D and construction for an ambitious ultra- precision timing detector system for the High-Luminosity Large Hadron Collider. Since 2013, she has initiated a program on AI/ML for the acceleration of discovery in elementary particle physics with exchanges and applications in other science domains. She has forged collaborations with quantum science and technology researchers, targeting the embedding of science problems in current and future quantum computing, networking, and communication testbeds. She has been working with the Department Of Energy and partnering government agencies on the National Quantum Initiative and the Quantum Internet Blueprint.