He is a fellow of the American College of Cardiology, American College of Physicians, and The Society for Cardiac Angiography and Interventions, and is a member of the Cardiovascular Health Advisory Panel to the Commissioner of Health of the State of New Jersey. He has participated in many clinical trials, serving as the lead investigator of the international, multicenter ESSENCE trial, ACUTE I, ACUTE II, TETAMI, SEPIA-PCI, and Compassion PAS, and was the co-lead investigator for the PRISM trial and Partners.

Dr. Cohen has authored or coauthored more than 400 articles including 200 peer-reviewed, original papers. He has been a member of the editorial boards of Journal of the American College of Cardiology, American Heart Journal, American Journal of Cardiology, Journal of Invasive Cardiology, and the Journal of Thrombosis and Thrombolysis.