Dymphna Margriet Ouwens

Cardiovascular disease is a common characteristic of type 2 diabetes. We propose that alterations in the secretory profile of the inflamed and expanded epicardial adipose tissue contribute to the pathogenesis of diabetes-related heart disease. Research in our team focuses on the detrimental effects of secretory products from epicardial adipose tissue on insulin action and contractile function, and aims to identify novel targets and biomarkers for insulin sensitivity.