Michelle A.M. Vis

Research profile Michelle Vis is a doctoral candidate (PhD) in Orthopaedic Biomechanics (OPB) under the supervision of Prof. Dr. Keita Ito and Dr. Sandra Hofmann. Her current research focusses on the development of a miniaturized in vitro model to study bone remodeling using human cells. In the future, such a model could be used to replace animal models for drug testing, mimicking a true human response. This multidisciplinary project covers a broad range of topics and techniques, such as tissue culture, bone remodeling, microfluidics, biomechanics, histology and microscopy, and cell interactions and behavior. Academic background Michelle Vis studied Biomedical Engineering at Eindhoven University of Technology where she received her BSc degree in 2016. At the same university, she obtained her MSc degree in 2019 in the Orthopaedic Biomechanics research group of Keita Ito. During her graduation project supervised by Dr. Sandra Hofmann, she focused on promoting vascularization in bone tissue engineered constructs. As part of her MSc degree, she completed an internship at the Christchurch Regenerative Medicine and Tissue Engineering group (CReaTE) at Otago University in Christchurch, New Zealand. She worked on silk fibroin hydrogels for cartilage tissue engineering applications. In 2019, she joined the Orthopaedic Biomechanics group as a PhD-student investigating bone remodeling by creating in vitro mini bones.