Main research fields are: study of phenotypic and molecular markers of normal and neoplastic lymphohematopoietic cells; histopathogenetic role of Epstein-Barr virus infection in systemic and primary cerebral non-Hodgkin's lymphoma and in Hodgkin's lymphoma; pathogenetic mechanisms of chronic myeloproliferative diseases; role of telomerase in the pathogenesis and in the progression of glial neoplasms; phenotypic and molecolar characteristics of cancer stem cells for the tailored therapy of glioblastoma. He is author of more than 430 peer-reviewered papers (total impact factor > 1650).