Our intestines are home to countless viruses, bacteria, fungi, and worms, which together make up the gut multibiome. Members of this multibiome help to regulate normal functions for our health, such as digestion and immune system development. However, disruptions to the intestinal ecosystem are associated with multiple inflammatory diseases. My research investigates how members of the multibiome interact with each other and the host to coordinate immune responses to viruses. We are also exploring how viral infections, diet, and the gut multibiome can together contribute to the development of multiple sclerosis, with the ultimate goal of informing prevention and therapy.