Research Interest Dr. Fried’s research is concentrated in two areas: the association of decreased kidney function with adverse outcomes in older individuals, including cardiovascular disease, functional decline and change in body composition; and progression of kidney disease, in particular diabetic nephropathy. Dr Fried was the Chair of a VA sponsored multi-center study on combination ACEI/ARB vs. ARB monotherapy on progression of diabetic nephropathy and is currently the chair of the steering committee for the NIDDK CKD pilot study consortium.