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My research focuses on the design and uses of magnetic nanoparticles, near infrared fluorescent (NIRF), and magneto/optical probes for a wide range of questions in biology, chemistry and physics. I have developed nanoparticles that are detectable by MRI and NIRF (magneto/optical probes), and demonstrated their use as pre-operative MR contrast agents and intra-operative optical probes in important clinical applications including lymph node delineation and brain tumor delineation. A second area I am involved with is the development of annexin V based probes for imaging apoptosis, which plays a crucial in the pathology and treatment of disease. Annexin V is used to image the induction of apoptosis by chemotherapy, to predict long-term chemotherapeutic efficacy early in the course of treatment.
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JOURNAL OF MEDICINAL CHEMISTRYno. 4 (2024): 2559-2569
Acta Pharmaceutica Sinica Bno. 1 (2022): 308-315
Ran Cheng,Masayuki Fujinaga,Jing Yang,Jian Rong,Ahmed Haider,Daisuke Ogasawara,Richard S. Van,Tuo Shao,Zhen Chen,Xiaofei Zhang, Erick R. Calderon Leon,Yiding Zhang,
METABOTROPIC GLUTAMATE RECEPTOR TECHNOLOGIES (2021): 23-37
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