Lai Chan - Department of Laboratory Medicine and

基本信息

Career Trajectory

Bio

Talented researcher with specialization in hematology/oncology, cellular metabolism, chemical biology and a passion for developing targeted therapies. Highly collaborative scientist known for ability to design in vitro and in vivo experiments that drive the development of novel efficacy and PD relationships in cancer models. Published writer and presenter who thrives in team environments.

Research Interests

Papers共 221 篇Author StatisticsCo-AuthorSimilar Experts

By YearBy Citation主题筛选期刊级别筛选合作者筛选合作机构筛选

Therapeutic Targeting Tudor Domains in Leukemia Via CRISPR-Scan Assisted Drug Discovery

Anthony K. N. Chan,Li Han,Christopher D. Delaney,Xueer Wang,Elizaveta Mukhaleva,Mingli Li,Lu Yang,Sheela Pangeni Pokharel,Nicole Mattson, Michelle Garcia, Bintao Wang,Xiaobao Xu,Leisi Zhang, Priyanka Singh, Zeinab Elsayed,Renee Chen,Benjamin Kuang,Jinhui Wang,Yate-Ching Yuan,Bryan Chen,Lai N. Chan,Steven T. Rosen,David Horne,Markus Muschen,Jianjun Chen,Nagarajan Vaidehi,Scott A. Armstrong,Rui Su,Chun-Wei Chen

SCIENCE ADVANCESno. 8 (2024)

Cited0Views0WOSSCIENCEBibtex

STAT5-Feedback Controls Distinct Metabolic States for Dynamic Transitions Between Cellular Activation and Quiescence in Acute Lymphoblastic Leukemia

Kohei Kume,Zhengshan Chen,Mark E. Robinson,Lai N. Chan,Etienne Leveille,Kadriye Nehir Cosgun,Zhangliang Cheng,David Fonseca Arce,Dhruv Khanduja,Thomas Graeber,Markus Muschen

Blood（2023）

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Dynamic Recruitment of Inhibitory Complexes Controls Oncogenic Signaling in B-Cell Malignancies

Ruifeng Sun,Jaewoong Lee,Mark E. Robinson,Kohei Kume,Ning Ma,Kadriye Nehir Cosgun,Lai N. Chan, Irina Antoshkina,Dhruv Khanduja,Etienne Leveille,Samuel G. Katz,Jianjun Chen,Elisabeth Paietta,Nagarajan Vaidehi,Markus Muschen

Bloodno. Supplement 1 (2023): 719-719

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Optogenetic Control of Oncogenic Signaling in B-Cell Malignancies

Kohei Kume,Jaewoong Lee,Zhangliang Cheng,Mark E. Robinson,Etienne Leveille,Kadriye Nehir Cosgun,Lai N. Chan,Yanzhi Feng, David Fonseca,Dhruv Khanduja,Derek Toomre,Markus Muschen

Bloodno. Supplement 1 (2023): 4138-4138

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Supplementary Data from in Vivo Antitumor Effect of a Novel Inhibitor of Protein Geranylgeranyltransferase-I

Jie Lu,Lai Chan,Hannah D.G. Fiji,Russell Dahl,Ohyun Kwon,Fuyuhiko Tamanoi

crossref（2023）

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Dynamic phosphatase-recruitment controls B-cell selection and oncogenic signaling

Jaewoong Lee,Mark E. Robinson,Ruifeng Sun,Kohei Kume,Ning Ma,Kadriye Nehir Cosgun,Lai N. Chan,Etienne Leveille,Huimin Geng,Vivasvan S. Vykunta,Brian R. Shy,Alexander Marson,Samuel Katz,Jianjun Chen,Elisabeth Paietta,Eric Meffre,Nagarajan Vaidehi,Markus Müschen

bioRxiv the preprint server for biology (2023)

Cited37Views0WOSBibtex

-Catenin Engages IKZF Factors to Control Lymphopoiesis

Kadriye Nehir Cosgun,Huda Jumaa,Mark E. Robinson, Liang Xu,Gang Xiao,David Fonseca Arce,Dhruv Khanduja,Lai N. Chan,Jaewoong Lee,Hilde Schjerven,Julia Jellusova,Markus Muschen

JOURNAL OF IMMUNOLOGYno. 1 (2023)

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Immunoglobulin Light Chains Control Permissiveness to Malignant B-Cell Transformation by RAS-Pathway Lesions

Lai N. Chan,Kohei Kume,Christian Hurtz,Mark E. Robinson,Kadriye Nehir Cosgun,Markus Muschen

Bloodno. Supplement 1 (2023): 2974-2974

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