My main research interests focus around immunogenetics and immunotherapy where I have published more than 500 papers to date. In the former area, we are mainly working on trying to understand the molecular basis of a variety of primary immunodeficiency diseases, including IgA deficiency (the most common form of primary immunodeficiency in Sweden) and common variable immunodeficiency. In the latter area, we are trying to develop novel forms of passive immunity that we can use to treat our patients, utilizing antibodies from different sources. Lately, we have turned to using genetically modified lactic acid bacteria as factories for producing antibody fragments in vivo and although most work has been performed in animal models, we are now preparing for clinical trials.