Katherine High

基本信息

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职业迁徙

个人简介

My career has focused on pioneering work in the area of gene therapy, with a focus on basic, translational, and clinical investigation in gene therapy.

研究兴趣

论文共 565 篇作者统计合作学者相似作者

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Gene and Cell Therapy in 2023: Rich Pipeline, Slimming Resources

Katherine A. High

Molecular Therapyno. 1 (2024): 3-4

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Hemophilia B and Gene Therapy: A New Chapter with Etranacogene Dezaparvovec

Xavier M. Anguela,Katherine A. High

BLOOD ADVANCES（2024）

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Patterns of joint bleeds in patients with hemophilia b following fidanacogene elaparvovec adeno-associated virus gene therapy

J. E. J. Rasko,A. Chhabra,J. M. Ducore,L. A. George,A. Giermasz,K. High, C. E. McGuinn, A. O'Brien,J. Rupon,B. J. Samelson-Jones, L. M. Smith,S. K. Sullivan,J. M. Teitel,I. Winburn

HAEMOPHILIA (2023): 113-114

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Trial by "Firsts": Clinical Trial Design and Regulatory Considerations in the Development and Approval of the First AAV Gene Therapy Product in the United States

Kathleen Z. Reape,Katherine A. High

Cold Spring Harbor perspectives in medicine（2023）

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Rationally Designed Cardiotropic AAV Capsid Demonstrates 30 Fold Higher Efficiency in Human vs Porcine Heart

Anna P. Tretiakova, Tugba Guven-Ozkan,Ferzin Sethna,Stacy Webb, Youjun Chen,Timothy D. Henry,Eugene Chung, Sheila Mikhail,Scott Hammond,Katherine A. High,Roger J. Hajjar,R. Jude Samulski

MOLECULAR THERAPY（2022）

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Long-term effect of voretigene neparvovec on the full-field light sensitivity threshold test of patients with RPE65 mutation-associated inherited retinal dystrophy: Post hoc analysis of Phase I trial data

Daniel Chung,Kathleen Reape,Katherine A. High,Sue Lacey,Daniel Viriato,John Grigg

INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE（2022）

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Functional Assessment of T Cell Responses to AAV8 Empty Capsids in Healthy Volunteers

Holly Schroeder,Lloyd Johnston, Eisha Clyde,Md Mahmudul Hasan, Bethany Kuszlewicz,Ross Fraser, Tanika Williamson, Greg Gojanovich, Paul Greback-Clarke,Tamara Zekovic,Jacob Smith,Katherine High,David Favre,Takashi Kei Kishimoto,Peter Traber,Shari Gordon,Richard J. Samulski

MOLECULAR THERAPY（2022）

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Analysis of Vector Performance in Patient Heart Biopsy for Congestive Heart Failure Provides Support for Rationally Designed Capsids

F. Sethna, T. Ozkan, S. Webb,K. Haghighi, Y. Chen, S. Hammond, P. Moullier, M. O'Callaghan,E. Kranias, T. Henry,E. Chung, A. P. Tretiakova, S. Mikhail,K. A. High,R. J. Hajjar,R. J. Samulski

HUMAN GENE THERAPY（2022）

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Factor IX Assay Discrepancies in the Setting of Liver Gene Therapy Using a Hyperfunctional Variant Factor IX‐Padua