Research Summary
My aim is to understand the patterns of how genetic variants influence complex traits. This involves questions such as how strong is the overall influence of genetics, and do disease subtypes differ in terms of their genetic risk factors? My current focus is to compare the genetic basis of traits across different populations, such as Africans and Europeans, using polygenic methods.
Additionally, I conduct studies to identify variants or genetic elements affecting traits. I was involved in several break-through discovery studies for cancer susceptibility loci. I also work on different aspects of cancer risk prediction.
I collaborate with research groups at the Wellcome Trust Sanger Institute, the University of Cambridge, UCL and the German Cancer Research Center (DKFZ).