Karl H. Weisgraber mainly focuses on Apolipoprotein E, Biochemistry, Apolipoprotein B, Lipoprotein and Endocrinology. His Apolipoprotein E study incorporates themes from LDL receptor, Very low-density lipoprotein, Receptor and Cholesterol. His Cholesterol research incorporates elements of Genetics and Disease. His Biochemistry research is multidisciplinary, incorporating perspectives in Alzheimer's disease and Cell biology. His Apolipoprotein B research is multidisciplinary, incorporating elements of Membrane and Neurodegeneration. His work in Endocrinology tackles topics such as Internal medicine which are related to areas like In vivo, In vitro, Chemical modification and Proteolysis.