Karina R Bortoluci

基本信息

Career Trajectory

Bio

The main focus of my lab is understanding the molecular basis of innate immune recognition by using the experimental models of Salmonella typhimurium and Trypanosoma cruzi infections.

Research Interests

Papers共 82 篇Author StatisticsCo-AuthorSimilar Experts

By YearBy Citation主题筛选期刊级别筛选合作者筛选合作机构筛选

Caspase-1/11 Controls Zika Virus Replication in Astrocytes by Regulating Glycolytic Metabolism

Ingrid S. Farias, Guilherme Ribeiro,Isaú H. Noronha,Jean P. S. Peron, Pedro M. Moraes Vieira,Jose C. Alves-Filho,Karina R. Bortoluci

crossref（2024）

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Three Main SCFAs Mitigate Lung Inflammation and Tissue Remodeling Nlrp3-Dependent in Murine HDM-Induced Neutrophilic Asthma

Barbara S. S. Tagé,Michelangelo B. Gonzatti,Rodolfo P. Vieira,Alexandre C. Keller,Karina R. Bortoluci,Flávio Aimbire

INFLAMMATIONno. 4 (2024): 1386-1402

Cited0Views0WOSBibtex

Molecular Regulation of NAIP/NLRC4 Inflammasomes

Marcelo Pires Amaral,Laura Migliari Branco,Silvia Lucena Lage,Karina Ramalho Bortoluci

Inflammasome Biologypp.77-91, (2023)

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NAIP/NLRC4 Inflammasome Participates in Macrophage Responses to Trypanosoma Cruzi by a Mechanism That Relies on Cathepsin-Dependent Caspase-1 Cleavage

Marcelo Pires Amaral, Felipe Daniel Cardoso, Ingrid Sancho de Farias, Rafael Queiroz de Souza,Kely Catarine Matteucci,Ana Claudia Torrecilhas,Karina Ramalho Bortoluci

Frontiers in immunology (2023)

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Lysicamine Reduces Protein Kinase B (AKT) Activation and Promotes Necrosis in Anaplastic Thyroid Cancer

Mariana Teixeira Rodrigues, Ana Paula Picaro Michelli, Gustavo Felisola Caso, Paloma Ramos de Oliveira,Dorival Mendes Rodrigues-Junior,Mirian Galliote Morale,Joel Machado Junior,Karina Ramalho Bortoluci,Rodrigo Esaki Tamura,Tamiris Reissa Cipriano da Silva,Cristiano Raminelli,Eric Chau,Biana Godin,Jamile Calil-Silveira,Ileana G. Sanchez Rubio

Pharmaceuticals（2023）

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Lysosomal cathepsins act in concert with Gasdermin-D during NAIP/NLRC4-dependent IL-1β secretion

Laura Migliari Branco,Marcelo Pires Amaral,Henning Boekhoff,Ana Beatriz Figueiredo de Lima,Ingrid Sancho Farias,Silvia Lucena Lage,Gustavo José Silva Pereira,Bernardo Simões Franklin,Karina Ramalho Bortoluci

Cell Death Dis（2022）

Cited3Views0WOSNATUREBibtex

Drug Repurposing in Chagas Disease: Chloroquine Potentiates Benznidazole Activity Against Trypanosoma Cruzi in Vitro and in Vivo

Ramendra P. Pandey,Marilda Savoia Nascimento,Caio Haddad Franco,Karina Bortoluci,Marcelo Nunes Silva,Bianca Zingales,Daniel Gibaldi,Leda Castano Barrios,Joseli Lannes-Vieira,Leonardo Moro Cariste,Jose Ronnie Vasconcelos,Carolina Borsoi Moraes,Lucio H. Freitas-Junior,Jorge Kalil,Laura Alcantara,Edecio Cunha-Neto

Antimicrobial agents and chemotherapy（2022）

Cited5Views0WOSBibtex

Lysosomal cathepsins act in concert with Gasdermin-D during NAIP/NLRC4-dependent IL-1 secretion

Laura Migliari Branco,Marcelo Pires Amaral,Henning Boekhoff,Ana Beatriz Figueiredo de Lima,Ingrid Sancho Farias,Silvia Lucena Lage,Gustavo Jose Silva Pereira,Bernardo Simoes Franklin,Karina Ramalho Bortoluci

CELL DEATH & DISEASE（2022）

Cited1Views0Bibtex

Extracellular vesicles derived from head and neck squamous cells carcinoma inhibit NLRP3 inflammasomes

Luiza Zainotti Miguel Fahur Bottino,Dorival Mendes Rodrigues-Junior, Ingrid Sancho de Farias,Laura Migliari Branco,N. Gopalakrishna Iyer,Gabriela Estrela de Albuquerque,André Luiz Vettore,Karina Ramalho Bortoluci

Current Research in Immunology (2021): 175-183

Cited7Views0WOSBibtex

Rapamycin Improves the Response of Effector and Memory CD8+ T Cells Induced by Immunization with ASP2 of Trypanosoma Cruzi

Barbara Ferri Moraschi,Isau Henrique Noronha,Camila Pontes Ferreira, Leonardo M. Cariste, Caroline B. Monteiro,Priscila Denapoli,Talita Vrechi,Gustavo J. S. Pereira,Ricardo T. Gazzinelli,Joseli Lannes-Vieira,Mauricio M. Rodrigues,Karina R. Bortoluci,Jose Ronnie C. Vasconcelos

FRONTIERS IN CELLULAR AND INFECTION MICROBIOLOGY（2021）

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Associate Professor

Papers共 82 篇Author StatisticsCo-AuthorSimilar Experts