Josée Dupuis, Ph.D, is a Professor and Chair of the Department of Epidemiology, Biostatistics and Occupational Health at McGill University. She previously held the position of Chair of Biostatistics at Boston University School of Public Health, and prior to that, she was a senior statistical geneticist at Genome Therapeutics Corporation, a small biotech company. She has extensive experience in the development and application of methods for mapping complex traits. Her methodological work has included genome-wide significance level, mapping of quantitative traits in experimental organisms, and robust quantitative trait linkage and association analysis methods in extended pedigrees. Her recent work involves the development of rare variant association tests in families and approaches to detect gene x gene and gene x environment interactions. She is involved in the Framingham Heart Study, collaborating on projects to identify genes influencing diabetes-related traits, pulmonary function, and biomarkers of inflammation.