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个人简介
José V. Castell. PhD in Biochemistry and MD in Medical Biochemistry, Graduate in Pharmacy. Postdoctoral at the ETH-Zürich and Max-Planck Institut, Göttingen. Invited professor at the Biochemisches Institut de Univesität Freiburg. Emeritus Professor of the Chair of Medical Biochemistry and Molecular Biology at the Faculty of Medicine of Valencia where he also reads a postgraduate course on Molecular Toxicology and Clinical Immunology. Head of the Unit of Experimental Hepatology at the Research Institute of the University Hospital La Fe (Valencia). Ex-Director of the Medical Research Center of the University Hospital La Fe (Valencia).
In 1990, Professor Castell was given the International Award of the European Federation of Pharmaceutical Industries (Heidelberg 1990) for the development of cultured human hepatocytes to investigate the hepatotoxic risk of new drugs to man.
His major research interests include: in vitro drug metabolism and hepatotoxicity, drug induced liver injury in clinics, cell reprogramming to hepatocytes, cell therapy with human hepatocytes and PSC-derived hepatocytes. He has authored 410 papers, including scientific articles published in relevant international journals, book chapters and several reviews.
His current research interest involve the use of metabolomics to assess drug hepatotoxicity in the clinics and in vitro (drug development, metabolism and toxicity).
Former member of the Scientific Advisory Committee of the European Center for Validation of Alternative Methods (ECVAM), Scientific Committee of INVITOX, and Scientific Committee ILSI.
Prof. Castell has been actively involved in over 25 EU research projects; and has served as coordinator in 3 of them.
研究兴趣
论文共 451 篇作者统计合作学者相似作者
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APPLIED SPECTROSCOPY REVIEWSno. 4 (2024): 578-599
MICROCHEMICAL JOURNAL (2024)
ANALYTICA CHIMICA ACTA (2024)
International Journal of Molecular Sciencesno. 10 (2024): 5203
Walter Zobl,Annette Bitsch,Jonathan Blum,Jan J. W. A. Boei,Liliana Capinha,Giada Carta,Jose Castell, Enrico Davoli, Christina Drake,Ciaran P. Fisher,Muriel M. Heldring,Barira Islam,Paul Jennings,Marcel Leist, Damiano Pellegrino-Coppola,Johannes P. Schimming,Kirsten E. Snijders,Laia Tolosa,Bob van de Water,Barbara M. A. van Vugt-Lussenburg,Paul Walker,Matthias M. Wehr,Lukas S. Wijaya,Sylvia E. Escher
ALTEX-ALTERNATIVES TO ANIMAL EXPERIMENTATIONno. 2 (2024): 302-319
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCESno. 5 (2024)
Stem cellsno. 11 (2023): 1076-1088
Archives of Toxicologyno. 6 (2023): 1723-1738
In Analysis (2023)
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作者统计
#Papers: 453
#Citation: 23477
H-Index: 70
G-Index: 139
Sociability: 7
Diversity: 4
Activity: 32
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