Jose E Manautou

My research interests are on biochemical and genetic determinants of susceptibility to liver toxicants. The focus of the research in my laboratory is on the role of drug transporters in the disposition of hepatotoxic agents and how changes in the expression and function of these transporters alter susceptibility to drug hepatotoxicity. My laboratory also continues to study the mechanistic basis of protection against acetaminophen hepatotoxicity by treatment with peroxisome proliferators.