基本信息
views: 9
Career Trajectory
Bio
My research program investigates the physiological regulation of arterial contractility and systemic blood pressure by ion channels expressed in smooth muscle and endothelial cells. My laboratory also examines pathological alterations in ion channels that are associated with cardiovascular diseases, including hypertension and stroke. Ion channels that we currently study include TRP, KV, ANO1 and CaV1.2 proteins. We use a broad range of techniques that incorporates the use of a molecular, biochemical, cellular, and functional approaches, making the research translational. Methods used in the laboratory include novel cell-specific gene knockout and cardiovascular disease models, RT-PCR, Western blotting, biotinylation, FRET, RNAi, co-IP, immunofluorescence, patch-clamp electrophysiology, membrane potential recording, intracellular Ca2+imaging, arterial myography and blood pressure telemetry.
Research Interests
Papers共 237 篇Author StatisticsCo-AuthorSimilar Experts
By YearBy Citation主题筛选期刊级别筛选合作者筛选合作机构筛选
时间
引用量
主题
期刊级别
合作者
合作机构
MICROCIRCULATIONno. 4 (2024)
Somasundaram Raghavan,Masuma Akter Brishti, Angelica Bernardelli,Alejandro Mata-Daboin,Jonathan H. Jaggar,M. Dennis Leo
Physiologyno. S1 (2023)
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICAno. 31 (2023): e2303238120-e2303238120
The Journal of physiologyno. 14 (2023): 3275-3296
Science signalingno. 811 (2023)
Load More
Author Statistics
#Papers: 237
#Citation: 7293
H-Index: 50
G-Index: 81
Sociability: 6
Diversity: 3
Activity: 27
Co-Author
Co-Institution
D-Core
- 合作者
- 学生
- 导师
Data Disclaimer
The page data are from open Internet sources, cooperative publishers and automatic analysis results through AI technology. We do not make any commitments and guarantees for the validity, accuracy, correctness, reliability, completeness and timeliness of the page data. If you have any questions, please contact us by email: report@aminer.cn