Jon Travers - Oncology IMED Biotech Unit, AstraZeneca

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Aurora B inhibition promotes a hyper-polyploid state and continued endomitotic cycles in RB and p53 defective cells

Shivam Vora, Ariel Andrew, Ramyashree Prasanna Kumar,Deborah Nazareth,Madushan Fernando,Mathew JK Jones,Yaowu He,John D. Hooper,Nigel AJ McMillan,Jelena Urosevic,Jamal Saeh,Jon Travers,Brian Gabrielli

biorxiv（2024）

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Aurora B Inhibitors Promote RB Hypophosphorylation and Senescence Independent of P53-Dependent CDK2/4 Inhibition

Shivam Vora, Ariel Andrew, Ramyashree Prasanna Kumar,Deborah Nazareth,Alexis Bonfim-Melo,Yoon Lim, Xin Yee Ong,Madushan Fernando,Yaowu He,John D. Hooper,Nigel A. J. McMillan,Jelena Urosevic,Jon Travers,Jamal Saeh,Sharad Kumar,Mathew J. K. Jones,Brian Gabrielli

CELL DEATH & DISEASEno. 11 (2024)

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Supplementary Fig 3 from TSR-033, a Novel Therapeutic Antibody Targeting LAG-3, Enhances T-Cell Function and the Activity of PD-1 Blockade In Vitro and In Vivo

Srimoyee Ghosh,Geeta Sharma,Jon Travers,Sujatha Kumar,Justin Choi,H. Toni Jun,Marilyn R. Kehry,Sridhar Ramaswamy,David Jenkins

openalex（2023）

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Abstract 2803: Pharmacokinetics and Pharmacodynamics of the Novel OMA1 Activator BTM 3566 in a Mouse Model of Diffuse Large B-cell Lymphoma

Azadeh Bagherzadeh, Jennifer Baker, Charlotte Bennett, Mi-Young Lee, Natalia Pacheco,Bhavisha Patel,Kevin Stewart,Jon Travers,Michael Stocum,Todd Hembrough,Matthew Kostura

Cancer Researchno. 7_Supplement (2023): 2803-2803

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Supplementary Fig 2 from TSR-033, a Novel Therapeutic Antibody Targeting LAG-3, Enhances T-Cell Function and the Activity of PD-1 Blockade In Vitro and In Vivo

Srimoyee Ghosh,Geeta Sharma,Jon Travers,Sujatha Kumar,Justin Choi,H. Toni Jun,Marilyn Kehry,Sridhar Ramaswamy,David Jenkins

crossref（2023）

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Supplementary Table S5 from Cells Lacking the RB1 Tumor Suppressor Gene Are Hyperdependent on Aurora B Kinase for Survival

Matthew G. Oser, Raquel Fonseca,Abhishek A. Chakraborty, Rachel Brough,Alexander Spektor,Rebecca B. Jennings,Abdallah Flaifel,Jesse S. Novak,Aditi Gulati,Elizabeth Buss,Scott T. Younger,Samuel K. McBrayer, Glenn S. Cowley,Dennis M. Bonal,Quang-De Nguyen,Laura Brulle-Soumare,Paula Taylor, Stefano Cairo,Colm J. Ryan,Elizabeth J. Pease,Kim Maratea,Jon Travers, David E. Root, Sabina Signoretti, David Pellman,Susan Ashton, Christopher J. Lord, Simon T. Barry, William G. Kaelin

crossref（2023）

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Supplementary Figure 1 from Targeting BCL2 Overcomes Resistance and Augments Response to Aurora Kinase B Inhibition by AZD2811 in Small Cell Lung Cancer

Kavya Ramkumar,Azusa Tanimoto,Carminia M. Della Corte,C. Allison Stewart,Qi Wang,Li Shen,Robert J. Cardnell,Jing Wang,Urszula M. Polanska,Courtney Andersen,Jamal Saeh,J. Elizabeth Pease,Jon Travers,Giulia Fabbri, Carl M. Gay,Jelena Urosevic,Lauren A. Byers

crossref（2023）

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Supplementary Table 2 from TSR-033, a Novel Therapeutic Antibody Targeting LAG-3, Enhances T-Cell Function and the Activity of PD-1 Blockade in Vitro and in Vivo

Srimoyee Ghosh,Geeta Sharma,Jon Travers,Sujatha Kumar,Justin Choi,H. Toni Jun,Marilyn R. Kehry,Sridhar Ramaswamy,David Jenkins

openalex（2023）

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