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个人简介
RESEARCH INTERESTS
Phenotypic Sceening, Axon Regeneration, and Drug Discovery
Transcription factors in Axon Growth
Our focus is on understanding and overcoming barriers to axon regeneration after injury to the central nervous system (CNS). We use various strategies to identify and manipulate molecular targets to promote this regeneration. When Dr. Vance Lemmon and I established our joint lab in 2003, we adopted two core technologies: phenotypic screening and transcriptomics. This combination was powerful and resulted in the identification of KLF family members as important regulators of CNS axon regeneration (Moore et al, 2010, Science, 326: 298; Blackmore et al, 2012, PNAS (USA) 109: 7517). We also did extensive work on other transcription factors such as STAT3 and Jun family members (Smith et al, 2011, Mol Cell Neurosci 46: 32; Lerch et al, 2014, Mol Cell Neurosci, 59: 97; Luo et al, 2016, Cell Rep, 15: 398; Mehta et al, 2016, Exp Neurol, 280: 115; Danzi et al, 2018, Mol Cell Neurosci 92: 114).
研究兴趣
论文共 171 篇作者统计合作学者相似作者
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Kar Men Mah,Wei Wu,Hassan Al-Ali,Yan Sun,Qi Han,Ying Ding, Melissa Munoz,Xiao-Ming Xu,Vance P. Lemmon,John L. Bixby
J. Russell Huie, Hannah Radabaugh, Kenneth Fond,Romana Vavrek,Michael Chiu, Anastasia Keller,John Gensel,Ubbo Visser,John Bixby,Vance Lemmon,Jeffrey Grethe,Maryann Martone,
JOURNAL OF NEUROTRAUMAno. 15-16 (2023): A29-A30
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Kar Men Mah,Wei Wu,Hassan Al-Ali,Yan Sun,Qi Han,Ying Ding, Melissa Muñoz,Xiao-Ming Xu,Vance P Lemmon,John L Bixby
Experimental neurology (2023): 114669-114669
JOURNAL OF RESEARCH ADMINISTRATIONno. 1 (2022): 144-161
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