John I. Trujillo - Departments of Medicinal Chemistry, Pfizer Global Research and Development

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Discovery, Characterization, and Structure of a Cell Active PAD2 Inhibitor Acting Through a Novel Allosteric Mechanism

Laura J. Byrnes, Won Young Choi,Paul Balbo,Mary Ellen Banker,Jeanne Chang, Shi Chen,Xuemin Cheng, Yang Cong, Jeff Culp, Hongxia Di,Matt Griffor,Justin Hall,Xiaoyun Meng,Barry Morgan,James J. Mousseau, Jennifer Nicki, Thomas O'Connell,Simeon Ramsey,Alex Shaginian,Suman Shanker,John Trujillo,Jinqiao Wan,Fabien Vincent, Stephen W. Wright,Felix Vajdos

ACS chemical biologyno. 10 (2024): 2186-2197

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Structural Basis for CCR6 Modulation by Allosteric Antagonists

David Jonathan Wasilko,Brian S. Gerstenberger,Kathleen A. Farley,Wei Li,Jennifer Alley,Mark E. Schnute,Ray J. Unwalla, Jorge Victorino, Kimberly K. Crouse,Ru Ding,Parag V. Sahasrabudhe,Fabien Vincent,Richard K. Frisbie,Alpay Dermenci,Andrew Flick,Chulho Choi, Gary Chinigo,James J. Mousseau,John I. Trujillo,Philippe Nuhant, Prolay Mondal,Vincent Lombardo,Daniel Lamb, Barbara J. Hogan, Gurdeep Singh Minhas,Elena Segala,Christine Oswald,Ian W. Windsor,Seungil Han,Mathieu Rappas,Robert M. Cooke,Matthew F. Calabrese,Gabriel Berstein, Atli Thorarensen,Huixian Wu

Nature Communications（2024）

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Early Process Development of PF-07054894, a Squaramide-Based Antagonist of C–C Chemokine Receptor Type 6 (CCR6)

Gary M. Chinigo,Emma L. Mcinturff,Scott W. Bagley,Richard W. Barnhart,David C. Blakemore, Lu Han,Taegyo Lee,Javier Magano,J. Christopher McWilliams,Sebastien Monfette,James J. Mousseau, Senliang Pan,Dylan Pedro,Hahdi H. Perfect, Jeffrey W. Raggon, Peter R. Rose,John Sagal,John I. Trujillo, Jared Van Haitsma,Michael G. Vetelino, Xiaojing Helen Yang

Organic process research & development (2024)

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Macrocyclic Retinoic Acid Receptor-Related Orphan Receptor C2 Inverse Agonists

Mark E. Schnute,John I. Trujillo,Katherine L. Lee,Ray Unwalla,Felix F. Vajdos,Bjorn Kauppi,Philippe Nuhant,Andrew C. Flick,Kimberly K. Crouse,Yajuan Zhao, Amanda Samuel,Vincent Lombardo,Alexandria P. Taylor,Amy L. Brault,John D. Knafels,Michael L. Vazquez,Gabriel Berstein

ACS Medicinal Chemistry Letters（2023）

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Demonstration of a Multikilogram-Scale Birch Reduction and Evaluation of Alternative Synthetic Routes to a Ketalized Cyclohexene Derivative

Adam E. Goetz,Joel Arcari,Scott W. Bagley,Robert Hicklin, Liangxue Jin, Zuxi Jin, Xinnan Li,Zhiqing Liu,J. Christopher McWilliams,Mihir D. Parikh, Tyler Potter, William J. Smith, Lijie Sun,John Trujillo, Pan Wang, Xin Zhao

ORGANIC PROCESS RESEARCH & DEVELOPMENT（2023）

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Synthesis of Multisubstituted Pyridines Via Nickel Catalysis

Paul Richardson,John I. Trujillo

Synfactsno. 09 (2021): 0973-0973

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Multicomponent Approach to Functionalized Pyrazoles

John I. Trujillo, Paul G. Richardson

Synfactsno. 11 (2021): 1197

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Sulfonium-Salt Based Trifluoromethylating Reagent Permits Multiple Reactivity Paradigms

John I. Trujillo,Paul Richardson

Synfactsno. 01 (2021): 0018-0018

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Photocatalytic Hydrocarboxylation in Flow for Β-Lactone Synthesis

Paul Richardson,John I. Trujillo

Synfactsno. 05 (2021): 0595-0595

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Practical Kilogram Synthesis of (S)-1-benzyl-4-bromo-3-methyl-1,2,3,6-tetrahydropyridine

Vincent M. Lombardo,Louise Bernier,Ming Z. Chen,William Farrell,Andrew Flick,Philippe Nuhant,Neal W. Sach,Yong Tao,John Trujillo

ORGANIC PROCESS RESEARCH & DEVELOPMENT（2021）

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