In 2001, I started my own research group and worked on development of novel vaccination and cellular strategies for the treatment of cancer, all of which were translated to clinical trials.

Outside of NKI and LUMC, I have been chair of the Working Party Immunotherapy for Oncology from 2008 – 2016. Within ESMO, I fulfilled the position of scientific chair of the ESMO IO meeting from 2016-2019, was scientific chair of the ESMO 2020 annual meeting, and I am Editor-in-Chief of ESMO Journal IOTECH, starting in 2018.