基本信息
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Career Trajectory
Bio
John Dick is a Senior Scientist at the Princess Margaret Cancer Centre and McEwen Stem Cell Institute, University Health Network, Professor of Molecular Genetics, University of Toronto and Co-Leader, Acute Leukemia, Translational Research Initiative, Ontario Institute for Cancer Research, Toronto. He is recognized for developing a system for transplanting normal and malignant human hematopoietic cells into immune-deficient mice and identifying and characterizing normal and leukemic human stem cells. His contributions have been recognized through election as a Fellow of The American Association for Cancer Research Academy (2016); Fellow of the Royal Society of London, UK (2014); Fellow of the Royal Society of Canada (2004) and numerous prestigious awards at the national and international level including the Dameshek Prize (2005) and the Thomas Prize (2009) from the American Society of Hematology; the Clowes Memorial Award from American Association for Cancer Research (2008); and AACR-Pezcoller Prize (2020) from American Association for Cancer Research;and AACR-Pezcoller Prize (2020) fromAmerican Association for Cancer Research;the Noble Prize from National Cancer Institute of Canada (2000); the Diamond Jubilee Award (2007) (with Drs. J.E. Till and E.A. McCulloch) from the National Cancer Institute of Canada; International KFJ Prize (2017) from Rigshospitalet, University of Copenhagen; Gold Leaf Prize for Discovery (2017) from the Canadian Institutes of Health Research; Tobias Award (2017) from The International Society for Stem Cell Research, USA; The KEIO Medical Science Prize, (2017) KEIO University, Tokyo, Japan; Special Achievement Award, (2018)Miami Winter Symposium, Miami, USA; ISSCR Award for Innovation (2019) from The International Society for Stem Cell Research; Dr. Chew Wei Memorial Prize in Cancer Research, (2019) University of British Columbia (UBC) Faculty of Medicine.
Dr. Dick's research has revolutionized the study of normal and leukemic human stem cells. Two of the most important achievements were developing a system for transplanting normal and malignant human hematopoietic cells into immune-deficient mice; and using this method to identify and characterize both normal and leukemic human stem cells. His lab established that only a small proportion of human leukemic cells were capable of initiating human leukemia within the immune-deficient mice. Purifiying these leukemia-initiating cells provided direct evidence for the cancer stem cell hypothesis.
Dr. John Dick has achieved groundbreaking findings in the areas of hematopoiesis and cancer. Through his work, he has pioneered the field of cancer stem cell biology, transformed our views of the origin and nature of cancer, and laid the foundation for new approaches to cancer therapy.
Research Interests
Papers共 571 篇Author StatisticsCo-AuthorSimilar Experts
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medRxiv (Cold Spring Harbor Laboratory) (2024)
CoRR (2024)
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Helena Boutzen,Alex Murison, Alexa Oriecuia, Suraj Bansal,Christopher Arlidge,Jean C. Y. Wang,Mathieu Lupien,Kerstin B. Kaufmann,John E. Dick
Leukemiano. 10 (2024): 2090-2101
Robert Vanner,Suraj Bansal, Marco Buttigeig,Andy Zeng,Yitong Yang, Darryl Chan,Vincent Rondeau, Carsten Muller-Tidow, Michael Rauh,Steven Chan,Andreas Trumpp,John Dick
Experimental Hematology (2024): 104575
Amanda Tajik,Emily Tsao,Brendon Seale,Soheil Jahangiri, Belma Abidin,Lina Liu,Zaldy Balde, He Tian (Tony) Chen,Nicholas Wong,Ava Keyvani Chahi,Pratik Joshi,Steven Moreira,Curtis W. McCloskey,Shahbaz Khan,Helena Boutzen,Cassandra Wong,Suraj Bansal,Andy G. X. Zeng,Stefan Aigner,Yu Lu,John E. Dick,Thomas Kislinger,Rama Khokha,Mark D. Minden,Gene W. Yeo,Anne-Claude Gingras,Kristin J. Hope
Experimental Hematology (2024)
Robert J. Vanner,Suraj Bansal, Marco M. Buttigeig,Andy G.X. Zeng,Vincent Rondeau, Darryl Y. Chan,Michelle Chan-Seng-Yue,Liqing Jin,Jessica McLeod,Elisa Donato, Patrick Stelmach,Caitlyn Vlasschaert,Yitong Yang, Aarushi Gupta, Sofia Genta, Enrique Sanz Garcia, Liran Shlush, Mauricio Ribeiro,Marcus O. Butler,Sagi Abelson,Mark Minden,Steven M. Chan, Michael J. Rauh,Andreas Trumpp,John E Dick
crossref(2024)
Joana Lima Araujo,Elvin Wagenblast,Veronique Voisin,Jessica McLeod,Olga I Gan,Suraj Bansal,Liqing Jin,Amanda Mitchell, Blaise Gratton, Sarah Cutting,Andrea Arruda,Monica Doedens,Jose-Mario Capo-Chichi,Sagi Abelson,Mark D Minden,Jean CY Wang,Manuel Areias Sobrinho-Simoes,Perpetua Pinto-do-O,Eric Lechman,John E Dick
crossref(2024)
David Kealy, Ruth Ellerington,Suraj Bansal,Andy G.X. Zeng,Jessie J.F. Medeiros, Katie A. West, Nicole-Mae Blacknell, Catherine A. Hawley, Jakub Lukaszonek, Richard Gawne, Hwei Minn Khoo, Gillian Caalim, Bryce Drylie, Jenny Chatzigerou, Bianca Rodriguez Lima Ferreira, Adele K Fielding,Guanlin Wang, David G. Kent,Bethan Psaila,Adam Wilkinson, Andrew N. Holding, Ian S. Hitchcock, Andrew S. Mason,Vikas Gupta,John E. Dick,Katherine S. Bridge
biorxiv(2024)
Mohsen Hosseini,Veronique Voisin,Ali Chegini,Angelica Varesi,Severine Cathelin,Dhanoop Manikoth Ayyathan,Alex C H Liu,Yitong Yang, Vivian Wang, Abdula Maher, Eric Grignano,Julie A Reisz,Angelo D'Alessandro,Kira Young,Yiyan Wu,Martina Fiumara,Samuele Ferrari,Luigi Naldini,Federico Gaiti,Shraddha Pai,Aaron D Schimmer,Gary D Bader,John E Dick,Stephanie Z Xie,Jennifer J Trowbridge,Steven M Chan
Research square (2024)
biorxiv(2024)
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Author Statistics
#Papers: 571
#Citation: 80549
H-Index: 102
G-Index: 283
Sociability: 8
Diversity: 0
Activity: 3
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