I am principal investigator of of the Translational Cancer Pathology Lab which aims to understand the determinants of short and long-term outcomes in patients with colorectal cancer. In particular, the relationship between the local and systemic inflammatory responses, tumour microenvironment and cell signalling with a view to taking such knowledge into the routine clinical management of colorectal cancer. Our overarching aim is to develop novel treatment strategies to establish a personalised medicine approach for colorectal cancer. I am also director of INCISE which seeks to transform polyp surveillance by developing a comprehensive risk stratification tool which will, for the first time, predict polyp recurrence by utilising the latest developments in digital pathology, machine learning and next generation sequencing.