Jessica L Martin

My Ph.D. research is focused on delineating the adaptive response of a protozoan parasite and purine auxotroph, Leishmania donovani, to the naturally-encountered purine limitation stress. Through a combination of global studies (proteomics, RNA-seq, and metabolomics) as well as targeted biochemical, genetic, and molecular biology techniques my research aims to understand how this parasite thrives in an ever-changing environment and to identify targets to exploit via therapeutic intervention.