Jeremy J. Edmunds - Pfizer Global Research and Development, Michigan Laboratories

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论文共 104 篇作者统计合作学者相似作者

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Targeting the Tyrosine Kinase 2 (TYK2) Pseudokinase Domain: Discovery of the Selective TYK2 Inhibitor ABBV-712

Eric Breinlinger,Stacy Van Epps,Michael Friedman,Maria Argiriadi, Ellen Chien, Gekleng Chhor,Marlon Cowart, Theresa Dunstan,Candace Graff, David Hardee,J. Martin Herold, Andrew Little,Richard Mccarthy,Julie Parmentier,Matthew Perham,Wei Qiu,Michael Schrimpf, Thomas Vargo,Matthew P. Webster,Fei Wu, Dawn Bennett,Jeremy Edmunds

Journal of medicinal chemistryno. 20 (2023): 14335-14356

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Untangling Perception and Reality: Small-Molecule TNF-α Inhibitors

Jeremy J. Edmunds

Medicinal Chemistry Reviews2019 Medicinal Chemistry Reviewspp.127-144, (2019)

引用2浏览0引用

Rank Ordering Compound Designs For Synthesis: When Do Methods Work And What Are Some Known Limitations

Kevin Cusack,Maria Argiriadi,Eric Breinlinger,Jeremy Edmunds,Dawn George,Friedman Michael,Michael Hoemann

ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY（2018）

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Prodrugs for Colon-Restricted Delivery: Design, Synthesis, and in Vivo Evaluation of Colony Stimulating Factor 1 Receptor (CSF1R) Inhibitors

Dawn M. George, Raymond J. Huntley,Kevin Cusack,David B. Duignan,Michael Hoemann,Jacqueline Loud,Regina Mario,Terry Melim, Kelly Mullen,Gagandeep Somal,Lu Wang,Jeremy J. Edmunds

PloS one（2018）

引用9浏览0WOS引用

Optimized Protein Kinase Cθ (pkcθ) Inhibitors Reveal Only Modest Anti-Inflammatory Efficacy in a Rodent Model of Arthritis

Dawn M. George,Eric C. Breinlinger,Maria A. Argiriadi,Yang Zhang,Jianfei Wang,Pratima Bansal-Pakala,David B. Duignan,Prisca Honore, QingYu Lang,Scott Mittelstadt,Lian Rundell,Annette Schwartz,Jiakang Sun,Jeremy J. Edmunds

Journal of Medicinal Chemistry（2014）

引用34浏览0WOS引用

Discovery of Selective and Orally Bioavailable Protein Kinase C theta (PKC theta ) Inhibitors from a Fragment Hit

Dawn M George,E C Breinlinger,Michael M Friedman,Yan Zhang,Jincheng Wang,Maria A Argiriadi, P Bansalpakala, Michael Barth,D B Duignan, P Honore,Q Lang,S Mittelstadt,Dominique Potin, L Rundell,J J Edmunds

Journal of Medicinal Chemistry（2015）

引用36浏览0引用

Discovery of selective and orally bioavailable protein kinase Cθ (PKCθ) inhibitors from a fragment hit

Dawn M George,Eric C Breinlinger,Michael Friedman,Yang Zhang,Jianfei Wang,Maria Argiriadi,Pratima Bansal-Pakala,Martine Barth,David B Duignan,Prisca Honore,QingYu Lang,Scott Mittelstadt,Dominique Potin,Lian Rundell,Jeremy J Edmunds

JOURNAL OF MEDICINAL CHEMISTRY（2015）

引用37浏览0WOS引用

Optimized Protein Kinase C theta (PKC theta ) Inhibitors Reveal Only Modest Anti-inflammatory Efficacy in a Rodent Model of Arthritis

Dawn M George,E C Breinlinger,Maria A Argiriadi,Yu Zhang, Jianbo Wang, P Bansalpakala,D B Duignan, P Honore,Q Lang,S Mittelstadt, L Rundell,Alan L Schwartz,Jian Sun,J J Edmunds

Journal of Medicinal Chemistry（2015）

引用31浏览0引用

Efficacy Of Abbv-105, A Selective And Irreversible Inhibitor Of Bruton'S Tyrosine Kinase (Btk), In Multiple Models Of Inflammation

Christian Goess,Candace Graff,Ting Ting Zhang,Gregory Preston,Richard Mccarthy,Matthew Perham,Jacqueline Loud,Christopher M. Harris,Sara Murdock,Erik Sampson,Michael Hoemann,Michael Friedman,Robert Talanian,Jeremy Edmunds,Andrew Long

ARTHRITIS & RHEUMATOLOGY（2015）

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