Our laboratory is interested in understanding the molecular mechanisms at play in the tug-of-war between viruses and the host. We want to understand how certain retroviruses enter cells and are then antagonized by innate immune molecules. Immunological recognition and restriction of viral pathogens is fundamental for fighting infectious disease.

Specifically, our research is focused on three areas:

Virus-cell and cell-cell fusion
How human innate immune restriction factors target HIV-1 replication and are counteracted by viral antagonists
Discovery of anti-viral agents