Dr. Roberts' research is interdisciplinary and involves fundamental, clinical, behavioral, global and epidemiological studies. He has been involved in several seminal studies of preeclampsia including the recognition of preeclampsia as involving endothelial dysfunction and being more than hypertension in pregnancy. He was protocol chair of the NIH trial (10,000 women) of vitamins C and E given to prevent preeclampsia. He currently heads the Global Pregnancy Collaboration, a consortium of 36 centers worldwide to facilitate collaborative research and research in low resource settings.