Mathematical Research Interests Dynamical systems: oscillations, coupled oscillators, and global stability analysis. Inverse problems: existence and uniquness of ODEs for given timecourses. Stochastic simulations: multi-timescale stochastic simulation algorithm. Parameter estimation of ODEs Biological Research Interests Circadian rhythms: transcriptioinal and post-transcriptional regulation, temperature compensation, and synchronization. p53 oscillation: γ-irradiation induced p53 pulses, and circadian rhythms of p53. Systems pharmacology: the effect of CK1𝛿/ɛ inhibitor PF-670462 on circadian phase. Synthetic biology: genetic oscillations in synthetic bacterial microconsortia Pharmacokinetics: estimation of drug metabolism kinetics