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个人简介
Strominger discovered how penicillin kills bacteria, and how the immune cells distinguish between “own” and “foreign” cells. In 1987, with colleague Don Wiley, he isolated, crystallized, and determined the 3D structures of two classes of MHC proteins. The resulting crystallography images showed that the proteins have a pronounced cleft packed with antigens, which exhibits antigens to killer T cells. This discovery clarified how the adaptive immune response is initiated. MHC proteins attack pathogens, implanted tissue, and the body’s own tissues in the case of autoimmune disease.
Professor Strominger has more than 30 awards to his name, including the Lasker Award and Japan Prize (both shared with Don Wiley). Former members of his laboratory include twelve Harvard professors, twelve National Academy of Science members, and two Nobel laureates.
Professor Strominger has more than 30 awards to his name, including the Lasker Award and Japan Prize (both shared with Don Wiley). Former members of his laboratory include twelve Harvard professors, twelve National Academy of Science members, and two Nobel laureates.
研究兴趣
论文共 1083 篇作者统计合作学者相似作者
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Fang Wang,Leonardo M. R. Ferreira, Andrew Mazzanti, Huaxiao Yu, Bowen Gu,Torsten B. Meissner,Qin Li,Jack L. Strominger
JOURNAL OF REPRODUCTIVE IMMUNOLOGY (2024)
Proceedings of the National Academy of Sciences of the United States of Americano. 31 (2024): e2404229121-e2404229121
crossref(2023)
crossref(2023)
Proceedings of the National Academy of Sciences of the United States of Americano. 9 (2021)
Henrieta Papuchova,Sarika Kshirsagar,Lily Xu, Hannah A. Bougleux Gomes,Qin Li,Vidya Iyer,Errol R. Norwitz,Jack L. Strominger,Tamara Tilburgs
Proceedings of the National Academy of Sciences of the United States of Americano. 27 (2020): 15772-15777
Cellno. 5 (2020): 1125-1139.e18
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作者统计
#Papers: 1091
#Citation: 120233
H-Index: 165
G-Index: 313
Sociability: 8
Diversity: 3
Activity: 6
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