基本信息
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Career Trajectory
Bio
Dr. Witztum's lab is interested in the mechanisms by which oxidation of lipoproteins causes atherosclerosis, and in particular how immune mechanisms contribute to this process.For more than 40 years, Dr. Witztum has made major contributions to the field of atherosclerosis. Alongside Dr. Daniel Steinberg, he first described the role of OxLDL in atherogenesis, providing fundamental information on its properties and evidence that it existed in experimental models and humans. He first showed that OxLDL was immunogenic, leading to both adaptive and innate immune responses to what he termed “oxidation-specific epitopes,” which fundamentally contributed to the concept that atherosclerosis was a chronic inflammatory disease. More recently, he has focused on defining the role of oxidized phospholipids in atherogenesis and inflammation in general.
Research Interests
Papers共 847 篇Author StatisticsCo-AuthorSimilar Experts
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期刊级别
合作者
合作机构
Amandine Chaix,Terry Lin, Bastian Ramms, Roy G. Cutler, Tiffani Le, Catherine Lopez, Phuong Miu,Antonio F. M. Pinto,Alan Saghatelian,Martin P. Playford,Nehal N. Mehta, Mark P. Mattson,Philip Gordts,Joseph L. Witztum,Satchidananda Panda
ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGYno. 9 (2024): 2069-2087
B30 SCARRED FOR LIFE TRANSLATIONAL RESEARCH IN INTERSTITIAL ABNORMALITIES AND LUNG FIBROSIS (2024)
A. Pessentheiner,N. Spann, C. Collins,B. Ramms, A. Chiang, Y. Wang, A. Quach,L. Booshehri,A. Hammond,C. Tognaccini,J. Latasiewicz,J. L. Witztum,H. Hoffman,N. Lewis,C. Glass,L. Bode,P. Gordts
JCI insight (2024)
Journal of the American College of Cardiologyno. 13 (2024): 1670
NEW ENGLAND JOURNAL OF MEDICINEno. 5 (2024): 476-477
Nature Reviews Cardiologyno. 3 (2024): 170-191
Journal of lipid researchno. 6 (2023): 100391-100391
Journal of clinical lipidologyno. 3 (2023): 406-411
Journal of Clinical Lipidology (2023)
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Author Statistics
#Papers: 847
#Citation: 99782
H-Index: 153
G-Index: 305
Sociability: 8
Diversity: 0
Activity: 2
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