Ivonne M.C.M. Rietjens mostly deals with Biochemistry, Quercetin, Pharmacology, Stereochemistry and Flavonoid. Carcinogen, Metabolite, Efflux, Glucuronidation and Metabolism are the primary areas of interest in her Biochemistry study. Her Quercetin research integrates issues from Internal medicine, Endocrinology, Quinone methide and Fatty acid.

Her Pharmacology research focuses on In vivo and how it relates to Glycol ethers. Her research integrates issues of Catechol, Substrate, Regioselectivity and Hydroxylation in her study of Stereochemistry. Her Flavonoid research includes themes of Catechin and Polyphenol.