Isao Okayasu

My research interests and work 1970-1974 Autopsy pathology (asplenia syndrome, fulminant hepatitis) and surgical pathology 1974-1980 Etiology and pathogenesis of the organ-specific autoimmune disease, particularly Hashimoto's disease (human pathology and experimental pathology) 1980-1994 Etiology and pathogenesis of ulcerative colitis and colitis-associated colorectal cancer (human pathology and experimental pathology) 1994-2010 Proposal of organ-specific chronic inflammation-carcinoma sequence, its confirmation, and prevention; ulcerative colitis as a typical model 2021-present Translational Research: Clinical usefulness of prostaglandin E-major urinary metabolite for monitoring ulcerative colitis Development of anti-cancer drug targeted to cancer type-amino acid transporter (LAT1)