RENIN-ANGIOTENSIN SYSTEMS. Work has focussed on their role in regulating tissue (especially cardiac) growth, inflammatory responses (especially in the lung) and in the regulation of human (especially hypoxic) physical performance. Most recently, work continues in studying their role in metabolic regulation.

ARTIFICIAL INTELLIGENCE AND BIG DATA ANALYTICS. We are working on largescale datasets with the goal of predicting patient decline.

HUMAN PHYSICAL PERFORMANCE. In 1998, we reported the first allele associated with such performance and have since reported others. Other work has addressed musculoskeletal remodelling and cardiac growth responses to exercise, as well as rthe mechanisms underpinning tendon injury and stress fractures.