许恒 - Institute of Materia Medica, Chinese Academy of Medical Sciences

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个人简介

主要进行小分子创新药物的设计与研发。

研究兴趣

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Cp*Ir‐Catalyzed C−H Arylation of 2‐pyridones and 1‐isoquinolinones with Arylsilanes

Tongxu Su,Heng Xu,Yi Dong

ADVANCED SYNTHESIS & CATALYSISno. 9 (2024): 2109-2114

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Rational Design and Optimization of Novel 4-Methyl Quinazoline Derivatives As PI3K/HDAC Dual Inhibitors with Benzamide As Zinc Binding Moiety for the Treatment of Acute Myeloid Leukemia

Kehui Zhang,Rui Huang,Ming Ji,Songwen Lin,Fangfang Lai,Deyu Wu,Hua Tian, Jinhui Bi,Shouguo Peng, Jiaqi Hu,Li Sheng,Yan Li,Xiaoguang Chen,Heng Xu

European Journal of Medicinal Chemistry (2024): 116015-116015

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Discovery of Novel Photoswitchable Pd-L1 Inhibitors Toward Precision Cancer Immunotherapy

Yan Zhang, Jichen Guan,Haixiang Qi,Lei Huang,Hua Tian,Junyi Liu,Songwen Lin,Yi Dong,Fangfang Lai,Heng Xu

crossref（2024）

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Rhodium-catalyzed site-selective cross-couplings of indoles and pyridotriazoles through carbene insertion

Hua Tian,Xin Yang, Ge Shi,Heng Xu,Yi Dong

Chinese Chemical Letterspp.110434, (2024)

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Design, Synthesis, and Bioevaluation of Novel Reversibly Photoswitchable PI3K Inhibitors Based on Phenylazopyridine Derivatives Toward Light-Controlled Cancer Treatment

Yan Zhang, Jialing Deng,Hua Tian,Haixiang Qi,Tianning Xiong,Songwen Lin,Yi Dong,Lijun Luo,Deyu Wu,Kehui Zhang,Ming Ji,Tingting Du,Li Sheng,Xiaoguang Chen,Heng Xu

JOURNAL OF MEDICINAL CHEMISTRY（2024）

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Design, Synthesis and Biological Evaluation of a Novel PSMA-PI3K Small Molecule Drug Conjugate

Shouguo Peng,Haixia Li,Weilu Cui,Tianning Xiong, Jiaqi Hu,Haixiang Qi,Songwen Lin,Deyu Wu,Ming Ji,Heng Xu

RSC MEDICINAL CHEMISTRY (2024)

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Rhodium-Catalyzed C-H Arylation of Indoles with Arylsilanes at Room Temperature

Tingting Hou,Xin Wang, Deyu Wu,Xin Yang,Guang Li,Heng Xu,Yi Dong

The Journal of organic chemistryno. 22 (2024): 16406-16418

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Cp*IrIII-Catalyzed C8-Selective C-H Activation Enables Room-Temperature Direct Arylation of Quinoline N-Oxides with Arylsilanes

Hua Tian,Tingting Hou,Xin Yang,Heng Xu,Yi Dong

Journal of organic chemistryno. 23 (2023): 16365-16375

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S-72, a Novel Orally Available Tubulin Inhibitor, Overcomes Paclitaxel Resistance Via Inactivation of the STING Pathway in Breast Cancer

Zhenyan Hou,Songwen Lin,Tingting Du,Mingjin Wang,Weida Wang,Shen You,Nina Xue,Yichen Liu,Ming Ji,Heng Xu,Xiaoguang Chen

PHARMACEUTICALSno. 5 (2023)

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Rhodium-Catalyzed Regioselective Synthesis of N -Secondary Alkyl Indoles Via Intermolecular Cyclization of N -Nitrosoanilines and Unsymmetrical Alkynes

Yiting Chang,Tingting Hou,Yi Dong,Heng Xu

Synthesisno. 23 (2023): 3969-3980

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Heng Xu(许恒)

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论文共 57 篇作者统计合作学者相似作者