Harold I Saavedra - Ponce Health Sciences University

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Bio

I am Harold I. Saavedra, a Professor at Ponce Health Sciences University, which specializes in the study of health care disparities in Hispanics. My research involves understanding how centrosome and mitotic regulators initiate and sustain breast cancers.

Research Interests

Papers共 78 篇Author StatisticsCo-AuthorSimilar Experts

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Abstract C151: Single and Combined Inhibition of AURKA and AURKB Promotes a Decrease in the Expression of EMT Biomarkers and Transcription Factors in Triple-Negative Breast Cancer in Women of African Ancestry

Joel A. Orengo-Orengo, Melanie Cruz, Alexandra Aquino,Harold I. Saavedra

Cancer Epidemiology, Biomarkers &amp Prevention（2024）

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Abstract C141: Inactivating the Mitotic Kinases TTK and NEK2 As a Promising Approach for the Reduction of Metastasis in Triple-Negative Breast Cancer in Non-Hispanic Blacks and Hispanic/Latinas

Alexandra N Aquino-Acevedo, Ángel D. Colón-Burgos, Gretchen M. Albarrán-Acosta, Marileana Rodríguez-Ruiz, Joel A. Orengo-Orengo, Melanie E. Cruz- Robles,Harold I. Saavedra

Cancer Epidemiology, Biomarkers &amp Prevention（2024）

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Mitotic Kinases Are Emerging Therapeutic Targets Against Metastatic Breast Cancer

Alexandra N Aquino-Acevedo, Joel A Orengo-Orengo,Melanie E Cruz-Robles,Harold I Saavedra

Cell divisionno. 1 (2024): 21-21

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Sustained Shugoshin 1 Downregulation Reduces Tumor Growth and Metastasis in a Mouse Xenograft Tumor Model of Triple-Negative Breast Cancer

Shirley Jusino,Yainyrette Rivera-Rivera,Camille Chardón-Colón, Patricia C. Rodríguez-Rodríguez,Janeishly Román-González,Valeria S. Juliá-Hernández,Angel Isidro,Qianxing Mo,Harold I. Saavedra

Cell Division（2023）

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Shugoshin As a Key Mediator in the Metastasis of Triple Negative Breast Cancer

Valeria Julia Hernandez,Shirley Jusino, Rivera, Camille Chardon Colon, Rodriguez,Janeishly Roman Gonzalez,Angel Isidro,Harold I. Saavedra

JOURNAL OF CLINICAL ONCOLOGYno. 16 (2023)

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Ethnic and Racial-Specific Differences in Levels of Centrosome-Associated Mitotic Kinases, Proliferative and Epithelial-to-mesenchymal Markers in Breast Cancers

Yainyrette Rivera-Rivera,Geraldine Vargas,Neha Jaiswal,Angel Núñez-Marrero,Jiannong Li,Dung-Tsa Chen,Steven Eschrich,Marilin Rosa,Joseph O. Johnson,Julie Dutil, Srikumar P. Chellappan,Harold I. Saavedra

Cell Division（2022）

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Shugoshin‐1 Depletion Reduces Tumor Growth in Triple‐Negative Breast Cancer

Rodriguez,Shirley Jusino, Rivera, Camille Chardon Colon,Janeishly Roman Gonzalez,Harold Saavedra

FASEB JOURNAL（2022）

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Phosphorylation of the Retinoblastoma Protein at Serine 249 and the Cadherin Switch As Clinically Informative Biomarkers for the Discrimination Between Indolent and Aggressive Forms of Prostate Cancer

Sheila M. Valle Cortes, Pedro Santiago Cardona,Carlos Diaz Osterman,Harold Saavedra,Shannalee R. Martinez, Gilberto Ruiz Deya, Jaileene Perez Morales,Adam B. Murphy

CANCER RESEARCHno. 12 (2022)

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Abstract 6001: Phosphorylation of the Retinoblastoma Protein at Serine 249 and the Cadherin Switch As Clinically Informative Biomarkers for the Discrimination Between Indolent and Aggressive Forms of Prostate Cancer

Sheila M. Valle Cortes, Pedro Santiago Cardona,Carlos Diaz Osterman,Harold Saavedra,Shannalee R. Martinez, Gilberto Ruiz Deya, Jaileene Perez Morales,Adam B. Murphy

Cancer researchno. 12_Supplement (2022): 6001-6001

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The Nek2 Centrosome-Mitotic Kinase Contributes to the Mesenchymal State, Cell Invasion, and Migration of Triple-Negative Breast Cancer Cells

Yainyrette Rivera-Rivera,Mihaela Marina,Shirley Jusino,Miyoung Lee,Jaleisha Vélez Velázquez,Camille Chardón-Colón,Geraldine Vargas,Jaya Padmanabhan,Srikumar P. Chellappan,Harold I. Saavedra

Scientific Reports（2021）

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