Guido Janssen - Department of Chemistry and Pharmaceutical Sciences, Amsterdam Institute for Molecules;Systems (AIMMS),, VU University Amsterdam;Amsterdam Institute for Molecules, Medicines & Systems (AIMMS),, VU University Amsterdam

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New Dual Inhibitors of Bacterial Topoisomerases with Broad-Spectrum Antibacterial Activity and in Vivo Efficacy Against Vancomycin-Intermediate Staphylococcus Aureus

JOURNAL OF MEDICINAL CHEMISTRYno. 6 (2023): 3968-3994

引用2浏览0WOS引用

Discovery and Hit-to-Lead Optimization of Benzothiazole Scaffold-Based DNA Gyrase Inhibitors with Potent Activity Against Acinetobacter Baumannii and Pseudomonas Aeruginosa

JOURNAL OF MEDICINAL CHEMISTRY（2023）

引用9浏览0WOS引用

Development of Tyrphostin Analogues to Study Inhibition of the Mycobacterium Tuberculosis Pup Proteasome System*

Guido Janssen,Susan Zhang,Remco Merkx,Christa Schiesswohl,Champak Chatterjee,K. Heran Darwin,Paul P. Geurink,Gerbrand J. van der Heden van Noort,Huib Ovaa

ChemBioChem（2021）

引用3浏览0WOS引用

Escape from planarity in fragment-based drug discovery: A physicochemical and 3D property analysis of synthetic 3D fragment libraries

David J. Hamilton,Tom Dekker,Hanna F. Klein,Guido V. Janssen,Maikel Wijtmans,Peter O’Brien,Iwan J.P. de Esch

Drug Discov Today Technol（2020）

引用16浏览0WOS引用

Discovery and Optimization of Inhibitors for the Pup Proteasome System in Mycobacterium tuberculosis

Guido V. Janssen,Susan Zhang,Remco Merkx,Christa Schiesswohl,Champak Chatterjee,K. Heran Darwin,Huib Ovaa

biorxiv（2019）

引用1浏览0引用

Mycobacterium tuberculosis Proteasome Accessory Factor A (PafA) Can Transfer Prokaryotic Ubiquitin-Like Protein (Pup) between Substrates

Susan Zhang,Kristin E. Burns-Huang,Guido V. Janssen,Huilin Li,Huib Ovaa,Lizbeth Hedstrom,K. Heran Darwin

MBIO（2017）

引用22浏览0WOS引用

Microwave-assisted Diastereoselective Two-Step Three-Component Synthesis for Rapid Access to Drug-Like Libraries of Substituted 3-Amino-β-lactams

Guido V. Janssen, Joyce A. C. van den Heuvel, Rik P. Megens,Jorg C. J. Benningshof,Huib Ovaa

Bioorganic & Medicinal Chemistryno. 1 (2017): 41-49

引用6浏览0WOS引用

Stereoselective Syntheses of 2-Imidazolines

G V Janssen

mag（2015）

引用23浏览0引用

ChemInform Abstract: Stereoselective Synthesis of Β‐sulfinylamino Isocyanides and 2‐Imidazolines

Guido V. Janssen,Esther Vicente-Garcia,Wouter Vogel,J. Chris Slootweg,Eelco Ruijter,Koop Lammertsma,Romano V. A. Orru

ChemInform（2015）

引用7浏览0引用

ChemInform Abstract: Chemoselective Addition of Isocyanides to N‐tert‐Butanesulfinimines

Guido V. Janssen,Elwin Janssen,Christophe M. L. Vande Velde,Andreas W. Ehlers,J. Chris Slootweg,Eelco Ruijter,Koop Lammertsma,Romano V. A. Orru

ChemInform（2015）

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