Dr. Mills' research ranges across: 1) translating the cancer genome through mechanistic studies determining the role of genomic and other aberrations present in patient tumors, 2) identification and validation of therapeutic targets emphasizing mechanisms of resistance and rational combination therapy to overcome emerging resistance in evolving cancers, 4) developing, validating, and implementing molecular markers; and 5) integrating data through a cancer systems biology approach into robust predictive mathematical models. The overarching goal is to perform deep molecular analysis of each patient “to let the patient teach us what is important”.
Dr. Mills is recognized as one of the most highly quoted scientists in the world with over 1000 publications. He also holds more than 20 patents. His work has been continuously He is funded by multiple grants for over 30 years. Dr. Mills efforts have been recognized in the Komen Foundation’s Brinker Award for Scientific Excellence and the Finneran Family Prize for Translational Research. He has been very successful in supporting training, mentoring, and career development for young scientists including graduate students, fellows, and junior faculty. The majority of his trainees have developed successful research careers rising through the ranks to full professor, department chairs, and institute directors. Based on this role, Dr. Mills has been nominated for and awarded multiple mentoring awards, including the Stand Up 2 Cancer Laura Ziskin Prize for Mentoring.