He has served on Editorial Boards of The Journal of Physiology, Microcirculation and as Editorial Advisor for the Biochemical Journal. He is a member of the Translational Sciences Panel of Heart Research UK, Board of External Referees for the Biotechnology & Biological Sciences Research Council and College of Experts for the Medical Research Council - Physiological Systems & Clinical Sciences. He has previously served as Chair of the Translational Sciences Panel for Heart Research UK, Medical Panel of the Henry Smith Charity and on grant panels of the British Heart Foundation, Guy's & St. Thomas’ Hospital Charitable Foundation and Royal Society International Networks Panel. Professor Mann has published >160 research papers and coordinated >38 research symposia at international conferences.
Professor Mann’s Vascular Biology research group is investigating signalling cascades involved the transcriptional activation of Nrf2-targeted antioxidant defence genes in endothelial and smooth muscle cells in oxidative stress and vascular dysfunction in diseases such as ischemic stroke, atherosclerosis and gestational diabetes. and have demonstrated the health benefits of dietary sulforaphane as an activator of Nrf2-targeted antioxidant enzymes.