Gilles P. Van Wezel

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Discovery of Isoquinoline Sulfonamides As Allosteric Gyrase Inhibitors with Activity Against Fluoroquinolone-Resistant Bacteria

Alexander T. Bakker,Ioli Kotsogianni,Mariana Avalos, Jeroen M. Punt, Bing Liu, Diana Piermarini,Berend Gagestein,Cornelis J. Slingerland,Le Zhang,Joost J. Willemse, Leela B. Ghimire,Richard J. H. B. N. van den Berg,Antonius P. A. Janssen,Tom H. M. Ottenhoff,Constant A. A. van Boeckel,Gilles P. van Wezel,Dmitry Ghilarov,Nathaniel I. Martin,Mario van der Stelt

Nature Chemistry (2024)

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Nanorapids As an Analytical Pipeline for the Discovery of Novel Bioactive Metabolites in Complex Culture Extracts at the Nanoscale

Isabel Nunez Santiago,Nataliia V. Machushynets,Marija Mladic,Doris A. van Bergeijk,Somayah S. Elsayed,Thomas Hankemeier,Gilles P. van Wezel

COMMUNICATIONS CHEMISTRYno. 1 (2024)

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Divergence of Classical and C-Ring-Cleaved Angucyclines: Elucidation of Early Tailoring Steps in Lugdunomycin and Thioangucycline Biosynthesis

Aleksi Nuutila,Xiansha Xiao,Helga U. van der Heul,Gilles P. van Wezel,Pedro Dinis,Somayah S. Elsayed,Mikko Metsa''-Ketela''

ACS Chemical Biology（2024）

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Discovery and Derivatization of Tridecaptin Antibiotics with Altered Host Specificity and Enhanced Bioactivity

Nataliia V. Machushynets,Karol Al Ayed,Barbara R. Terlouw,Chao Du,Ned P. Buijs,Joost Willemse,Somayah S. Elsayed,Julian Schill,Vincent Trebosc,Michel Pieren,Francesca M. Alexander,Stephen A. Cochrane,Mark R. Liles,Marnix H. Medema,Nathaniel I. Martin,Gilles P. van Wezel

ACS Chemical Biologyno. 5 (2024): 1106-1115

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Biomimetic Total Synthesis and Paired Omics Identify an Intermolecular Diels-Alder Reaction As the Key Step in Lugdunomycin Biosynthesis

Michiel T. Uiterweerd,Isabel Nunez Santiago,Remco Havenith,Chao Du, Le Zhang,Helga van der Heul,Somayah Elsayed, Adri Minnaard,Gilles van Wezel

crossref（2024）

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The stomatin-like protein StlP organizes membrane microdomains to govern polar growth in filamentous actinobacteria under hyperosmotic stress

Dennis Claessen,Xiaobo Zhong,Sarah Baur,Veronique Ongenae, Guillermo Guerrero Egido,Shraddha Shitut,Chao Du,Erik Vijgenboom,Gilles van Wezel, Victor Carrion Brava,Ariane Briegel,Marc Bramkamp

crossref（2024）

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LogoMotif: a Comprehensive Database of Transcription Factor Binding Site Profiles in Actinobacteria

Hannah E. Augustijn, Dimitris Karapliafis, Kristy M. M. Joosten,Sébastien Rigali,Gilles P. van Wezel,Marnix H. Medema

Journal of Molecular Biologypp.168558-168558, (2024)

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Polyester Degradation by Soil Bacteria: Identification of Conserved BHETase Enzymes in Streptomyces

Jo-Anne Verschoor, Martijn R. J. Croese, Sven E. Lakemeier, Annemiek Mugge, Charlotte M. C. Burgers,Paolo Innocenti,Joost Willemse,Marjolein E. Crooijmans,Gilles P. van Wezel,Arthur F. J. Ram,Johannes H. de Winde

Communications biologyno. 1 (2024): 725-725

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CslA and GlxA from Streptomyces Lividans Form a Functional Cellulose Synthase Complex

Xiaobo Zhong,Simone Nicolardi,Ruochen Ouyang,Manfred Wuhrer,Chao Du,Gilles van Wezel,Erik Vijgenboom,Ariane Briegel,Dennis Claessen

APPLIED AND ENVIRONMENTAL MICROBIOLOGYno. 4 (2024)

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Taxonomic and Metabolic Diversity of Actinobacteria Isolated from Faeces of a 28,000-Year-old Mammoth

Doris A. van Bergeijk,Hannah E. Augustijn,Somayah S. Elsayed,Joost Willemse,Victor J. Carrion,Chao Du,Mia Urem,Lena V. Grigoreva,Maksim Y. Cheprasov,Semyon Grigoriev,Hans Jansen, Bas Wintermans, Andries E. Budding,Herman P. Spaink,Marnix H. Medema,Gilles P. van Wezel

ENVIRONMENTAL MICROBIOLOGYno. 2 (2024)

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