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Not only did my investigations provide a detailed account of the cellular pattern of physiologic angiogenesis, it was also coupled to a stereologic study, which related the growth of the capillaries within the corpus luteum to development of that tissue as a transient endocrine organ. This involved relating alterations in endothelial cell shape, surface area of endothelial cell membrane available for trans-capillary exchange and thinness of the endothelium to the functional demand of the surrounding steroid-secreting luteal cells.
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